During a recent podcast interview, I was asked an intriguing question: “If glucose is the brain’s preferred fuel, why isn’t more glucose better for the brain?“

It’s a fascinating question that highlights an important paradox about brain health! 

The answer lies in finding that “sweet spot” where your brain gets just the right amount of glucose to thrive – hence the title of my latest book. 

It’s not about avoiding sugar completely, but rather understanding how to create the right balance.

Why does your brain need the right amount of glucose? 

Did you know? While your brain is only 2% of your body weight, it uses 20-25% of your body’s glucose-derived energy!

Glucose mostly comes from the carbohydrates in our food – whether that’s fruits, vegetables, grains, or sugary treats. 

But just like a car engine needs the right amount and source of fuel to run smoothly, your brain needs balanced glucose levels – not too high, not too low.

Here are 3 reasons why high blood sugar can be damaging to your brain:

I covered this in more detail in my book “Sweet Spot for Brain Health” (page numbers in paranthesis) if you’re interested to delve deeper into this 

1️⃣ Guardian Gate Effects 

Your blood-brain barrier acts like a careful security system, protecting your brain from harmful substances (p.11). 

High blood sugar can damage this protective barrier, making it “leaky” and allowing unwanted substances to enter your brain. 

Think of it like heat loosening the mortar between bricks in a wall.

2️⃣ The Oxidative Storm 

When there’s too much glucose, your brain’s energy factories (mitochondria) can become overwhelmed. 

This creates excess “exhaust fumes” called reactive oxygen species (p.17-18). 

These harmful molecules can damage your brain cells – like rust forming on metal.

3️⃣ The Inflammation Connection 

High blood sugar triggers inflammation throughout your body, including your brain. 

This inflammation, combined with oxidative stress, can affect how well your brain cells communicate. 

It’s like having static on a phone line, making it harder for brain regions to work together effectively.

Question for you today 

What’s one small step you could take today to help keep your blood sugar levels in that sweet spot? 

Perhaps starting with a protein-rich breakfast (see nutrition strategies on p.55-71), or taking a short walk after meals (movement strategies on p.73-77)?

Wishing you balanced energy for your beautiful brain, 

Dr Sui Wong

PS – Want to learn more about how blood sugar affects your brain health? My book “Sweet Spot for Brain Health” goes deeper into these concepts. It’s not about sugar abstinence – it’s about understanding how to create an environment where your brain can thrive by maintaining that perfect balance. 

Readers have particularly enjoyed how it combines novel insights with practical strategies, including a 12-week action plan to help you implement these brain-healthy habits. Available on Amazon in paperback, ebook, and audiobook.